Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables unmethylated CpG binding activity. Involved in histone H3-K36 demethylation. Acts upstream of or within several processes, including chordate embryonic development; heart looping; and regulation of gene expression. Is active in chromatin. Is expressed in embryo; forebrain; and limb. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human KDM2A (lysine demethylase 2A).