Automated description from the Alliance of Genome Resources (Release 4.2.0)
Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Part of ubiquitin ligase complex. Is expressed in several structures, including branchial arch; ear; forelimb bud; heart; and notochord. Orthologous to human FBXO8 (F-box protein 8).