Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity and saccharopine dehydrogenase (NADP+, L-lysine-forming) activity. Acts upstream of or within L-lysine catabolic process. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in hyperlysinemia. Orthologous to human AASS (aminoadipate-semialdehyde synthase).