Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have G protein-coupled receptor binding activity; GTPase activator activity; and Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of cell death. Predicted to localize to cytosol and plasma membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in brain and heart. Orthologous to human ARHGEF1 (Rho guanine nucleotide exchange factor 1).