Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ADP binding activity and ATP binding activity. Involved in negative regulation of insulin secretion and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within glutamate secretion, neurotransmission and neuromuscular process. Part of protein-containing complex. Is active in plasma membrane. Is expressed in cerebral cortex; foregut-midgut junction; heart ventricle; and retina inner nuclear layer. Used to study hyperinsulinemic hypoglycemia and transient neonatal diabetes mellitus. Human ortholog(s) of this gene implicated in glucose metabolism disease (multiple) and hypertension. Orthologous to human ABCC8 (ATP binding cassette subfamily C member 8).