Automated description from the Alliance of Genome Resources
Predicted to have adenyl-nucleotide exchange factor activity and chaperone binding activity. Involved in several processes, including cellular response to mechanical stimulus; extrinsic apoptotic signaling pathway in absence of ligand; and muscle cell cellular homeostasis. Localizes to the Z disc. Used to study dilated cardiomyopathy 1HH. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and respiratory system. Orthologous to human BAG3 (BAG cochaperone 3).