Automated description from the Alliance of Genome Resources
Exhibits several functions, including chromatin binding activity; nuclear receptor activity; and transcription factor binding activity. Involved in several processes, including mammary gland development; regulation of defense response; and reproductive structure development. Localizes to the cytoplasm and nucleus. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); bone disease (multiple); breast cancer (multiple); and migraine. Orthologous to human ESR1 (estrogen receptor 1).