Automated description from the Alliance of Genome Resources (Release 8.1.0)
Enables toxin transmembrane transporter activity. Acts upstream of or within several processes, including bilirubin transport; glucuronoside transport; and mercury ion transport. Located in apical plasma membrane and intercellular canaliculus. Is active in cell surface; plasma membrane; and vesicle. Is expressed in foregut; genitourinary system; and liver and biliary system. Human ortholog(s) of this gene implicated in bile duct disease (multiple); bilirubin metabolic disorder (multiple); leukemia (multiple); liver disease (multiple); and lung non-small cell carcinoma. Orthologous to human ABCC2 (ATP binding cassette subfamily C member 2).
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