Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables canalicular bile acid transmembrane transporter activity. Involved in several processes, including canalicular bile acid transport; lipid homeostasis; and regulation of lipid metabolic process. Located in apical part of cell; intercellular canaliculus; and plasma membrane. Is expressed in liver. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).