Automated description from the Alliance of Genome Resources (Release 5.2.0)
A structural constituent of cytoskeleton. Predicted to be involved in positive regulation of vasoconstriction; regulation of cytoskeleton organization; and response to xenobiotic stimulus. Located in several cellular components, including brush border; condensed nuclear chromosome; and postsynaptic density. Is expressed in central nervous system; chondrocranium; gut; tail unsegmented mesenchyme; and vertebral axis musculature. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human ADD3 (adducin 3).