Automated description from the Alliance of Genome Resources
A structural constituent of cytoskeleton. Predicted to be involved in several processes, including actin filament bundle assembly; barbed-end actin filament capping; and positive regulation of vasoconstriction. Localizes to several cellular components, including the brush border; condensed nuclear chromosome; and postsynaptic density. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Is expressed in central nervous system; chondrocranium; gut; tail unsegmented mesenchyme; and vertebral axis musculature. Orthologous to human ADD3 (adducin 3).