Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Involved in several processes, including T cell activation; animal organ development; and cellular cation homeostasis. Localizes to several cellular components, including cytoplasmic vesicle; lysosome; and nucleus. Is expressed in several structures, including ciliary body; future brain; hemolymphoid system gland; metanephros; and optic choroid plus pigmented retinal epithelium. Used to study autosomal recessive osteopetrosis 1 and clubfoot. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).