Automated description from the Alliance of Genome Resources
Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Involved in several processes, including T cell activation; animal organ development; and cellular cation homeostasis. Localizes to several cellular components, including the cytoplasmic vesicle; lysosome; and plasma membrane. Used to study autosomal recessive osteopetrosis 1 and clubfoot. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).