Automated description from the Alliance of Genome Resources
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in defense response to virus. Predicted to localize to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in inflammatory bowel disease 14 and systemic lupus erythematosus. Is expressed in eye; ovary; telencephalon; and urinary system. Orthologous to human IRF5 (interferon regulatory factor 5).