Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables N-sulfoglucosamine sulfohydrolase activity and sulfuric ester hydrolase activity. Involved in heparan sulfate proteoglycan catabolic process. Acts upstream of or within determination of adult lifespan and motor behavior. Is active in lysosomal lumen. Used to study mucopolysaccharidosis III and mucopolysaccharidosis type IIIA. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIIA. Orthologous to human SGSH (N-sulfoglucosamine sulfohydrolase).