Automated description from the Alliance of Genome Resources
Exhibits SMAD binding activity and transcription corepressor activity. Involved in negative regulation of BMP signaling pathway; negative regulation of osteoblast differentiation; and regulation of SMAD protein signal transduction. Localizes to the cytoplasm. Is expressed in 1st branchial arch; genitourinary system; limb; sensory organ; and skeleton. Orthologous to human TOB1 (transducer of ERBB2, 1).