Automated description from the Alliance of Genome Resources (Release 4.1.0)
Predicted to enable ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including animal organ morphogenesis; apoptotic process; and protein ubiquitination. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including adrenal gland; genitourinary system; immune system; neural retina; and telencephalon. Orthologous to human CUL1 (cullin 1).