Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to contribute to ubiquitin protein ligase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; apoptotic process; and protein ubiquitination. Localizes to SCF ubiquitin ligase complex. Is expressed in several structures, including adrenal gland; genitourinary system; immune system; neural retina; and telencephalon. Orthologous to human CUL1 (cullin 1).