Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables cysteine-type endopeptidase activator activity involved in apoptotic process; identical protein binding activity; and protease binding activity. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in cytoplasm and nucleus. Predicted to be active in PML body and mitochondrion. Is expressed in several structures, including brain ventricular layer; incisor; inner cell mass; renal calyx; and submandibular gland primordium. Orthologous to human CASP8AP2 (caspase 8 associated protein 2).