Automated description from the Alliance of Genome Resources
Exhibits profilin binding activity. Involved in several processes, including cytoskeleton organization; presynapse to nucleus signaling pathway; and synaptic vesicle clustering. Localizes to the postsynaptic density and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein).