Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits profilin binding activity. Involved in several processes, including insulin secretion; presynapse to nucleus signaling pathway; and synaptic vesicle clustering. Localizes to postsynaptic density and presynaptic active zone cytoplasmic component. Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein).