Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including anterior/posterior axis specification; nervous system development; and regulation of gene expression. Localizes to the nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including central nervous system; endoderm; genitourinary system; gut; and respiratory system. Orthologous to human FOXA2 (forkhead box A2).