Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits MAP kinase kinase activity; protein serine/threonine kinase activity; and receptor tyrosine kinase binding activity. Involved in several processes, including protein phosphorylation; regulation of signal transduction; and tube morphogenesis. Localizes to postsynaptic density. Is expressed in several structures, including central nervous system; gut; metanephros; reproductive system; and respiratory system. Used to study Wolff-Parkinson-White syndrome. Human ortholog(s) of this gene implicated in frontometaphyseal dysplasia 2 and prostate cancer. Orthologous to human MAP3K7 (mitogen-activated protein kinase kinase kinase 7).