Automated description from the Alliance of Genome Resources
Exhibits MAP kinase kinase activity. Involved in several processes, including animal organ development; cell motility; and neurogenesis. Predicted to colocalize with the microtubule. Used to study cardiofaciocutaneous syndrome. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome; malignant glioma; pancreatic adenocarcinoma; renal cell carcinoma; and small intestine adenocarcinoma. Orthologous to human MAP2K1 (mitogen-activated protein kinase kinase 1).