Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits MAP kinase activity; MAP kinase kinase activity; and phosphotyrosine residue binding activity. Involved in several processes, including animal organ development; positive regulation of macromolecule metabolic process; and positive regulation of response to external stimulus. Localizes to cytosol; nucleus; and pseudopodium. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and nervous system. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3).