Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II complex binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including in utero embryonic development; photoreceptor cell maintenance; and regulation of cellular macromolecule biosynthetic process. Localizes to the condensed chromosome; cytoplasm; and nucleus. Colocalizes with the integrator complex. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Is expressed in several structures, including central nervous system; early conceptus; endocrine gland; gonad; and sensory organ. Orthologous to human ESRRB (estrogen related receptor beta).