Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables mitogen-activated protein kinase kinase binding activity and protein domain specific binding activity. Involved in negative regulation of protein dephosphorylation; positive regulation of dephosphorylation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in cytoplasm and microtubule. Is expressed in central nervous system and genitourinary system. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to several human genes including IGBP1 (immunoglobulin binding protein 1).