Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Acts upstream of or within chemotaxis; release of sequestered calcium ion into cytosol; and response to cytokine. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; immune system; intestine; and reproductive system. Orthologous to human XCR1 (X-C motif chemokine receptor 1).