Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have beta-catenin binding activity and gamma-catenin binding activity. Predicted to be involved in several processes, including activation of GTPase activity; negative regulation of canonical Wnt signaling pathway; and negative regulation of microtubule depolymerization. Predicted to colocalize with cytoplasmic microtubule and filamentous actin. Human ortholog(s) of this gene implicated in Sotos syndrome and complex cortical dysplasia with other brain malformations. Is expressed in several structures, including appendicular skeleton; axial skeleton; nervous system; and sensory organ. Orthologous to human APC2 (APC regulator of WNT signaling pathway 2).