Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in several processes, including eye development; negative regulation of transcription by RNA polymerase II; and nervous system development. Localizes to cytoplasm and nucleus. Is expressed in central nervous system; eye; and limb. Orthologous to human VAX2 (ventral anterior homeobox 2).