Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable PDZ domain binding activity; identical protein binding activity; and sodium:phosphate symporter activity. Involved in several processes, including calcium ion homeostasis; inorganic diphosphate transport; and response to sodium phosphate. Acts upstream of or within bone remodeling. Located in basolateral plasma membrane and vesicle. Is expressed in genitourinary system; ileum; skeleton; and tooth. Used to study hereditary hypophosphatemic rickets with hypercalciuria. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1).