Automated description from the Alliance of Genome Resources
Involved in cellular response to leukemia inhibitory factor and negative regulation of MAP kinase activity. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 17 with or without anosmia. Is expressed in several structures, including alimentary system; embryo mesenchyme; germ layer; limb; and nervous system. Orthologous to human SPRY4 (sprouty RTK signaling antagonist 4).