Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; neural retina development; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within retinal rod cell differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; face; hindlimb; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in idiopathic generalized epilepsy 15. Orthologous to human RORB (RAR related orphan receptor B).