Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of B cell activation; and response to bacterium. Localizes to the cytoplasm and nucleus. Used to study systemic lupus erythematosus. Is expressed in Peyer's patch; genitourinary system; immune system; lung; and spinal cord. Orthologous to human IKZF3 (IKAROS family zinc finger 3).