Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including cardiac muscle hypertrophy in response to stress; circulatory system development; and regulation of transcription by RNA polymerase II. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the Sin3 complex. Used to study aortic valve disease and tetralogy of Fallot. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human HEY2 (hes related family bHLH transcription factor with YRPW motif 2).