Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including cell adhesion molecule binding activity; protein tyrosine kinase binding activity; and transmembrane transporter binding activity. Acts upstream of or within negative regulation of osteoclast development and negative regulation of tumor necrosis factor-mediated signaling pathway. Located in nucleus; plasma membrane; and tight junction. Is expressed in several structures, including early conceptus; genitourinary system; inner ear; neural ectoderm; and tooth. Human ortholog(s) of this gene implicated in disease of metabolism and progressive familial intrahepatic cholestasis 4. Orthologous to human TJP2 (tight junction protein 2).