Automated description from the Alliance of Genome Resources
Predicted to have protein C-terminus binding activity; protein binding activity, bridging; and protein domain specific binding activity. Involved in TNFSF11-mediated signaling pathway and negative regulation of osteoclast development. Localizes to the nucleus; plasma membrane; and tight junction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 51; disease of metabolism; and progressive familial intrahepatic cholestasis 4. Is expressed in blastocyst; early embryo; genitourinary system; lower jaw tooth; and neural ectoderm. Orthologous to human TJP2 (tight junction protein 2).