Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including Toll-like receptor 2 binding activity; identical protein binding activity; and lipopeptide binding activity. Involved in defense response; positive regulation of interleukin-6 biosynthetic process; and positive regulation of tumor necrosis factor biosynthetic process. Predicted to localize to several cellular components, including Golgi apparatus; Toll-like receptor 1-Toll-like receptor 2 protein complex; and membrane raft. Is expressed in cerebral cortex and telencephalon. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; aspergillosis; asthma; leprosy; and pyelonephritis. Orthologous to human TLR1 (toll like receptor 1).