Automated description from the Alliance of Genome Resources
Predicted to have several functions, including Toll-like receptor 2 binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in defense response; positive regulation of interleukin-6 biosynthetic process; and positive regulation of tumor necrosis factor biosynthetic process. Predicted to localize to several cellular components, including the Golgi apparatus; Toll-like receptor 1-Toll-like receptor 2 protein complex; and membrane raft. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; aspergillosis; asthma; leprosy; and pyelonephritis. Orthologous to human TLR1 (toll like receptor 1).