Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits semaphorin receptor binding activity. Involved in several processes, including angiogenesis; negative regulation of cell-matrix adhesion; and regulation of actin cytoskeleton reorganization. Localizes to extracellular space. Is expressed in several structures, including hemolymphoid system gland; nervous system; nose; palatal shelf mesenchyme; and trunk mesenchyme. Human ortholog(s) of this gene implicated in CHARGE syndrome. Orthologous to human SEMA3E (semaphorin 3E).