Automated description from the Alliance of Genome Resources
Exhibits semaphorin receptor binding activity. Involved in several processes, including angiogenesis; negative regulation of cell-matrix adhesion; and regulation of actin cytoskeleton reorganization. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in CHARGE syndrome. Is expressed in several structures, including central nervous system; cochlea; nose; palatal shelf mesenchyme; and trunk mesenchyme. Orthologous to human SEMA3E (semaphorin 3E).