Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including ATP binding activity; extracellularly ATP-gated cation channel activity; and lipopolysaccharide binding activity. Involved in several processes, including organophosphate ester transport; positive regulation of secretion; and regulation of MAPK cascade. Localizes to several cellular components, including external side of plasma membrane; neuromuscular junction; and neuronal cell body. Is expressed in brain; heart; and metanephros. Orthologous to human P2RX7 (purinergic receptor P2X 7).