Automated description from the Alliance of Genome Resources (Release 3.1)
Exhibits granulocyte colony-stimulating factor binding activity. Involved in neutrophil chemotaxis and regulation of myeloid cell differentiation. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in several structures, including brain; dorsal aorta; early conceptus; liver; and reproductive system. Used to study hereditary neutrophilia. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; chronic neutrophilic leukemia; myelodysplastic syndrome; and severe congenital neutropenia. Orthologous to human CSF3R (colony stimulating factor 3 receptor).