Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have several functions, including ATP binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Involved in several processes, including regulation of endothelial cell differentiation; regulation of transcription by RNA polymerase II; and vasculature development. Predicted to localize to several cellular components, including BMP receptor complex; dendrite; and neuronal cell body. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia and pulmonary hypertension. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human ACVRL1 (activin A receptor like type 1).