Automated description from the Alliance of Genome Resources (Release 4.1.0)
Predicted to enable DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA-dependent DNA replication; double-strand break repair via break-induced replication; and regulation of chromatin silencing at telomere. Predicted to act upstream of or within DNA replication. Predicted to be located in centrosome; ciliary basal body; and nucleoplasm. Predicted to be part of DNA replication preinitiation complex. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; central nervous system; and limb. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Orthologous to human CDC45 (cell division cycle 45).