Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables 3-phosphoinositide-dependent protein kinase activity and protein kinase activator activity. Involved in several processes, including negative regulation of cardiac muscle cell apoptotic process; transmembrane receptor protein tyrosine kinase signaling pathway; and type B pancreatic cell development. Acts upstream of or within hyperosmotic response. Located in cytoplasmic vesicle and postsynaptic density. Is expressed in several structures, including central nervous system; early conceptus; gonad; hemolymphoid system gland; and retina. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to several human genes including PDPK1 (3-phosphoinositide dependent protein kinase 1).