Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable extracellular matrix protein binding activity and integrin binding activity. Involved in regulation of transforming growth factor beta activation. Acts upstream of or within several processes, including Langerhans cell differentiation; ganglioside metabolic process; and hard palate development. Part of integrin alphav-beta8 complex. Is expressed in several structures, including axial skeleton; hindlimb phalanx; nervous system; reproductive system; and sensory organ. Orthologous to human ITGB8 (integrin subunit beta 8).