Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits DNA binding activity; DNA-binding transcription factor activity; and p53 binding activity. Involved in several processes, including cerebrospinal fluid secretion; nervous system development; and regulation of intracellular signal transduction. Localizes to nucleus. Is expressed in brain; nose; tooth; and vibrissa. Used to study otitis media. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73).