Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables phosphatidylinositol-3,4,5-trisphosphate binding activity. Acts upstream of or within establishment of epithelial cell polarity and positive regulation of cell adhesion. Located in several cellular components, including adherens junction; bicellular tight junction; and ruffle. Is expressed in brain; neocortex; and telencephalon. Orthologous to human CYTH3 (cytohesin 3).