Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable calmodulin binding activity. Acts upstream of or within several processes, including embryonic heart tube left/right pattern formation; epithelial cilium movement involved in determination of left/right asymmetry; and protein localization to ciliary inversin compartment. Located in ciliary base and ciliary inversin compartment. Is expressed in several structures, including adrenal gland; brain; gut gland; hemolymphoid system; and skeletal musculature. Used to study nephronophthisis 2 and tetralogy of Fallot. Human ortholog(s) of this gene implicated in nephronophthisis 2. Orthologous to human INVS (inversin).