Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits calmodulin binding activity. Involved in several processes, including gamete generation; maintenance of centrosome location; and nervous system development. Localizes to cytoplasm; microtubule cytoskeleton; and midbody. Is expressed in several structures, including gonad; gut; hemolymphoid system gland; nervous system; and perichondrium. Used to study microcephaly. Human ortholog(s) of this gene implicated in microcephaly; primary autosomal recessive microcephaly; primary autosomal recessive microcephaly 5; and visual epilepsy. Orthologous to human ASPM (assembly factor for spindle microtubules).