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Gene Ontology Classifications
Symbol
Name
ID
Zfpm2
zinc finger protein, multitype 2
MGI:1334444

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Automated description from the Alliance of Genome Resources (Release 4.1.0)

Enables transcription corepressor activity. Involved in several processes, including negative regulation of female gonad development; positive regulation of cardiac muscle cell proliferation; and positive regulation of male gonad development. Acts upstream of or within several processes, including animal organ development; regulation of transcription by RNA polymerase II; and vasculogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; heart; reproductive system; trigeminal ganglion; and urinary system. Used to study congenital diaphragmatic hernia; tetralogy of Fallot; and tricuspid atresia. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).



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Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory