Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables transcription corepressor activity. Involved in several processes, including negative regulation of female gonad development; positive regulation of cardiac muscle cell proliferation; and positive regulation of male gonad development. Acts upstream of or within several processes, including animal organ development; regulation of transcription by RNA polymerase II; and vasculogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; heart; reproductive system; trigeminal ganglion; and urinary system. Used to study congenital diaphragmatic hernia; tetralogy of Fallot; and tricuspid atresia. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).