Automated description from the Alliance of Genome Resources
Exhibits C-X3-C chemokine binding activity; G protein-coupled receptor activity; and cytokine receptor activity. Involved in several processes, including leukocyte migration; nervous system development; and regulation of cellular biosynthetic process. Localizes to the cell surface. Used to study age related macular degeneration 12. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1).