Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA binding activity. Predicted to be involved in DNA methylation-dependent heterochromatin assembly; negative regulation of astrocyte differentiation; and negative regulation of transcription by RNA polymerase II. Localizes to cytoplasm; heterochromatin; and nuclear lumen. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MBD1 (methyl-CpG binding domain protein 1).