Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have voltage-gated chloride channel activity. Involved in regulation of body fluid levels and renal inner medulla development. Localizes to basolateral plasma membrane. Is expressed in early conceptus; inner ear; metanephros; and oocyte. Used to study nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in Bartter disease type 4b and sensorineural hearing loss. Orthologous to human CLCNKA (chloride voltage-gated channel Ka).