Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables (R)-carnitine transmembrane transporter activity. Involved in several processes, including (R)-carnitine transmembrane transport; response to tumor necrosis factor; and response to type II interferon. Acts upstream of or within several processes, including adult heart development; carnitine metabolic process; and carnitine transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including liver; metanephros; nasal cavity mucosa; spleen; and testis. Used to study systemic primary carnitine deficiency disease. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5).