Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have several functions, including RNA polymerase I core promoter sequence-specific DNA binding activity; Tat protein binding activity; and p53 binding activity. Involved in blastocyst hatching; cell differentiation; and negative regulation of cell population proliferation. Localizes to chromosome. Used to study atypical teratoid rhabdoid tumor. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 3; atypical teratoid rhabdoid tumor; neurilemmomatosis; and rhabdoid cancer. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1).